Structure of PDB 7s8e Chain A

Receptor sequence
>7s8eA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
REAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB7s8e Molecular mechanism of phosphopeptide neoantigen immunogenicity.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 R62 N63 I66 Y67 Q70 T73 E76 S77 L81 Y84 L95 Y99 Y116 T143 K146 W147 A150 E152 Q155 R156 Y159 W167 Y171 Y7 R62 N63 I66 Y67 Q70 T73 E76 S77 L81 Y84 L95 Y99 Y116 T143 K146 W147 A150 E152 Q155 R156 Y159 W167 Y171
External links
PDB RCSB:7s8e, PDBe:7s8e, PDBj:7s8e
PDBsum7s8e
PubMed37353482
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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