Structure of PDB 7s6v Chain A

Receptor sequence
>7s6vA (length=345) Species: 5671 (Leishmania infantum) [Search protein sequence]
MSLNAADAADERSRKEMDRFQVERMAGQGTFGTVQLGKEKSTGMSVAIKK
VIQDPRFRNRELQIMQDLAVLHHPNIVQLQSYFYTLGERDRRDIYLNVVM
EYVPDTLHRCCRNYYRRQVAPPPILIKVFLFQLIRSIGCLHLPSVNVCHR
DIKPHNVLVNEADGTLKLCDFGSAKKLSPSEPNVAYICSRYYRAPELIFG
NQHYTTSVDIWSVGCIFAEMMLGEPIFRGDNSAGQLHEIVRVLGCPSREV
LRKLNYNSKGIPWSSVFCDHSLKDAKEAYDLLSALLQYLPEDRMKPYEAL
CHPYFDELHDSATKLPNNKDLPEDLFRFLPSEIEVMSEAQKAKLV
3D structure
PDB7s6v Leishmania infantum Glycogen Synthase Kinase 3 beta bound to CGP60474
ChainA
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8II A G27 V34 A47 K49 M100 V103 H155 L158 C169 G27 V34 A47 K49 M100 V103 H155 L158 C169
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0044024 histone H2AS1 kinase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:7s6v, PDBe:7s6v, PDBj:7s6v
PDBsum7s6v
PubMed
UniProtA4HXQ3

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