Structure of PDB 7s47 Chain A

Receptor sequence
>7s47A (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
SHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAV
KKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLE
GGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRNIKSDSILLT
HDGRVKLSDFGFCAQVSKEVPRRKELVGTPYWMAPELISRLPYGPEVDIW
SLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFL
DRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNR
3D structure
PDB7s47 Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4)
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E329 G330 S331 N440 K442 D444 F461 G477 T478 Y480 W481 E507 E512 F516 M524 E30 G31 S32 N141 K143 D145 F162 G178 T179 Y181 W182 E208 E213 F217 M225
BS02 ANP A I327 F397 L398 L447 I28 F98 L99 L148
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7s47, PDBe:7s47, PDBj:7s47
PDBsum7s47
PubMed
UniProtO96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 (Gene Name=PAK4);
P18084

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