Structure of PDB 7s2m Chain A

Receptor sequence
>7s2mA (length=258) Species: 77133 (uncultured bacterium) [Search protein sequence]
QGMSKIFGIVNITTDSFSDGGLYLDTDKAIEHALHLVEDGADVIDLGAAS
SNPDTTEVGVVEEIKRLKPVIKALKEKGISISVDTFKPEVQSFCIEQKVD
FINDIQGFPYPEIYSGLAKSDCKLVLMHSVQRETNPEEVFTSMMEFFKER
IAALVEAGVKRERIILDPGMGFFLGSNPETSILVLKRFPEIQEAFNLQVM
IAVSRKSFLGKITGTDVKSRLAPTLAAEMYAYKKGADYLRTHDVKSLSDA
LKISKALG
3D structure
PDB7s2m Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics.
ChainA
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.15: dihydropteroate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HHR A D82 N101 I103 M125 D172 F178 A207 K211 R245 D84 N103 I105 M127 D167 F173 A202 K206 R240
Gene Ontology
Molecular Function
GO:0004156 dihydropteroate synthase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009396 folic acid-containing compound biosynthetic process
GO:0042558 pteridine-containing compound metabolic process
GO:0044237 cellular metabolic process
GO:0046654 tetrahydrofolate biosynthetic process
GO:0046656 folic acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:7s2m, PDBe:7s2m, PDBj:7s2m
PDBsum7s2m
PubMed37419898
UniProtQ8GJ22

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