Structure of PDB 7s0y Chain A

Receptor sequence
>7s0yA (length=542) Species: 1496 (Clostridioides difficile) [Search protein sequence]
GGMSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVEKYLK
LKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNL
HFVWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVES
AINDTLESFRENLNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENP
ELIIDDIVKTYLSNEYSKEIDELNTYIEESLNKITQNSGNDVRNFEEFKN
GESFNLYEQELVERWNLAAASDILRISALKEIGGMYLDVDMLPGIQPDLF
ESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEHFDMLDEEVQSSFES
VLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKDSYSSNL
IVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMM
ELGKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADL
RNFEISKTNISQSTEQEMASLWSFDDARAKAQFEEYKRNYFE
3D structure
PDB7s0y Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
ChainA
Resolution2.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
3.4.22.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D288 E515 D290 E517
BS02 UDP A V101 W102 I103 L265 S269 D286 D288 S518 L519 W520 V103 W104 I105 L267 S271 D288 D290 S520 L521 W522
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7s0y, PDBe:7s0y, PDBj:7s0y
PDBsum7s0y
PubMed34678063
UniProtP18177|TCDB_CLODI Toxin B (Gene Name=tcdB)

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