Structure of PDB 7rxq Chain A

Receptor sequence
>7rxqA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAG
VYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSS
SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVTET
YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGK
YQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQES
NIARTLARELAPDFYQPGPEYQKRR
3D structure
PDB7rxq Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
ChainA
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F8 W18 G21 K22 C29 T30 G31 P32 W42 G45 F46 E47 W54 S56 N58 G67 R69 K77 F8 W18 G21 K22 C29 T30 G31 P32 W42 G45 F46 E47 W54 S56 N58 G67 R69 K77
Gene Ontology
Cellular Component
GO:0030314 junctional membrane complex

View graph for
Cellular Component
External links
PDB RCSB:7rxq, PDBe:7rxq, PDBj:7rxq
PDBsum7rxq
PubMed35238659
UniProtQ9BR39|JPH2_HUMAN Junctophilin-2 (Gene Name=JPH2)

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