Structure of PDB 7rx2 Chain A

Receptor sequence
>7rx2A (length=615) Species: 451804 (Aspergillus fumigatus A1163) [Search protein sequence]
QENHHVDYVIRFNYGDIDTPEAIKKFEVLLLELSEVGLQTEVRQGDENSL
FVFVRAASKKKLKRAVYQSRVRDWLYGVRNTEPEPASSAKPQSEAERLLV
IYHLITVPKAEGGAGITPRHGEWKNVDAIFPLHDEETNRQCMREWSKKTF
LSTEDLDRIRNTFGEHVGFYFAFLQSYFRFLMFPAAFGFSCWLLLGSFSI
IYTVVNCLWCIVFIEYWKRQEEDLSCRWQTKGVSAVHEKRAEFKPEKEIR
VRGVFPATKRMYRQLLQVPFALLAAVALGAIIATCFAIEIFISEVYNGPL
KGYLVFIPTILVSALIPTMSAVLLTVATKLNDYENYETQDAYKVALTQKI
FVVNFITSYLPIILTAFVYVPFASRIVPYLDFSINPDRLRKQVIYFTVTA
QIVGFALETIVPFVKEDEARFLTRVRNEAELEDYDVTDDLREMCIQFGYL
ALFSPVWPLVPVSFLINNWVELRSDFFKICVECKRPWPQRADTIGPWLDS
LGFLSWVGSITSSALVYMFSNGHEGPNGEPTTIRCWALLLTIFFSEHLYL
IVRYAVRSALAKLEPPNTRRERIERFMMRKRYLDTVLSPTERFWMRQRGW
KESAEVGLSLITKAK
3D structure
PDB7rx2 TMEM16 scramblases thin the membrane to enable lipid scrambling.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0005245 voltage-gated calcium channel activity
GO:0005254 chloride channel activity
GO:0017128 phospholipid scramblase activity
Biological Process
GO:0017121 plasma membrane phospholipid scrambling
GO:0034220 monoatomic ion transmembrane transport
GO:0045332 phospholipid translocation
GO:0070588 calcium ion transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0032541 cortical endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rx2, PDBe:7rx2, PDBj:7rx2
PDBsum7rx2
PubMed35562175
UniProtQ4WA18

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