Structure of PDB 7rtj Chain A

Receptor sequence
>7rtjA (length=398) Species: 154 (Spirochaeta thermophila) [Search protein sequence]
TYTLVWKVWILAVTLYFAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLLLAPSRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLISVQRSA
TRILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRYLS
AFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLV
SKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEE
REVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIY
GPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFGEMALI
LRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQIQELAVRRKE
3D structure
PDB7rtj Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
ChainA
Resolution3.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A Y357 F366 G367 E368 R377 R418 Y335 F344 G345 E346 R355 R396
BS02 PGW A I144 L221 I122 L199
BS03 PGW A S102 G150 S157 S80 G128 S135
BS04 PGW A A209 L213 A187 L191
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7rtj, PDBe:7rtj, PDBj:7rtj
PDBsum7rtj
PubMed36376326
UniProtG0GA88

[Back to BioLiP]