Structure of PDB 7rtf Chain A

Receptor sequence
>7rtfA (length=395) Species: 154 (Spirochaeta thermophila) [Search protein sequence]
TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLAFLLAPSRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLISVQA
SATRILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRY
LSAFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIAS
LVSKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGY
EEREVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPV
IYGPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFGEMA
LILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQIQELA
3D structure
PDB7rtf Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A G367 R377 T378 A379 G347 R357 T358 A359
BS02 PGW A G167 Y170 F174 G147 Y150 F154
BS03 PGW A L34 F143 L25 F123
BS04 PGW A L109 I116 L89 I96
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rtf, PDBe:7rtf, PDBj:7rtf
PDBsum7rtf
PubMed36376326
UniProtG0GA88

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