Structure of PDB 7rsu Chain A

Receptor sequence

>7rsuA (length=756) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence]

MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEE
VKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKI
REHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGE
EFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKE
KDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWE
TGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTG
NLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENI
VYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIP
SLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRRIKILASSYYGYYGYA
RARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPG
ADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEE
GKITTGGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKL
SKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVIS
YIVLKGSGRIGDRAIPFDEFDPAKHKYDAEYYIENQVLPAVERILRAFGY
RKEDLR

3D structure

PDB

7rsu Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities.

Chain

Resolution

2.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	S348 G350 S383 Y384 E385 G386 V389 G495 G498 Y499 T590 K591 K593 W615 T676 R709 I710 G711 Y731 R743	S348 G350 S383 Y384 E385 G386 V389 G495 G498 Y499 T590 K591 K593 W615 T676 R709 I710 G711 Y731 R743
BS02	dna	A	D540 K592 G607 V611 R612 R613 E664 Q665 T667 R668 Y673 A675 H679	D540 K592 G607 V611 R612 R613 E664 Q665 T667 R668 Y673 A675 H679

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity

View graph for
Molecular Function

External links

PDB	RCSB:7rsu, PDBe:7rsu, PDBj:7rsu
PDBsum	7rsu
PubMed	34637287
UniProt	P77933\|DPOL_THEKO DNA polymerase (Gene Name=pol)

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