Structure of PDB 7rs3 Chain A

Receptor sequence
>7rs3A (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPIYSSMMGLLTNLADRELVHMINWAKRVPG
FVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGK
CVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKSLEE
KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKG
MEHLYSMKNVVPSYDLLLEMLDA
3D structure
PDB7rs3 Dual-mechanism estrogen receptor inhibitors.
ChainA
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7OR A L346 T347 A350 E353 L387 L391 F404 M421 I424 G521 L525 M528 V533 V534 P535 L30 T31 A34 E37 L71 L75 F88 M105 I108 G200 L204 M207 V210 V211 P212
External links
PDB RCSB:7rs3, PDBe:7rs3, PDBj:7rs3
PDBsum7rs3
PubMed34452998
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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