Structure of PDB 7rom Chain A

Receptor sequence
>7romA (length=255) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KPVLDPKRNDFQSFPLVEKTILTHNTSMYKFGLPHADDVLGLPIGQHIVI
KANINGKDITRSYTPTSLDGDTKGNFELLVKSYPTGNVSKMIGELKIGDS
IQIKGPRGNYHYERNCRSHLGMIAGGTGIAPMYQIMKAIAMDPHDTTKVS
LVFGNVHEEDILLKKELEALVAMKPSQFKIVYYLDSPDREDWTGGVGYIT
KDVIKEHLPAATMDNVQILICGPPAMVASVRRSTVDLGFRRSKPLSKMED
QVFVF
3D structure
PDB7rom Crystal structure of Saccharomyces cerevisiae NADH-cytochrome b5 reductase 1 (Cbr1) fragment (residues 28-284) bound to FAD
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.2.2: cytochrome-b5 reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A R90 S91 Y92 T93 L108 V109 Y112 T114 G115 N116 V117 S118 T156 A159 R61 S62 Y63 T64 L79 V80 Y83 T85 G86 N87 V88 S89 T127 A130
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0016491 oxidoreductase activity
GO:0016740 transferase activity
GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity
Biological Process
GO:0002098 tRNA wobble uridine modification
GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
GO:0017183 protein histidyl modification to diphthamide
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005886 plasma membrane

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Cellular Component
External links
PDB RCSB:7rom, PDBe:7rom, PDBj:7rom
PDBsum7rom
PubMed
UniProtP38626|NCB5R_YEAST NADH-cytochrome b5 reductase 1 (Gene Name=CBR1)

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