Structure of PDB 7rmv Chain A

Receptor sequence
>7rmvA (length=553) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MKYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMNIDAGTM
SPLEHGECFVLDDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAK
ERKGDYLGKTVQIVPHLTNAIQDWIERVAKIPVDDTGMEPDVCIIELGGT
VGDIESAPFVEALRQFQFKVGKENFALIHVSLVPVIHGEQKTKPTQAAIK
GLRSLGLVPDMIACRCSETLDKPTIDKIAMFCHVGPEQVVNVHDVNSTYH
VPLLLLEQKMIDYLHARLKLDEISLTEEEELLSKWKATTGNFDETVKIAL
VGKYTNLKDSYLSVIKALEHSSMKCRRKLDIKWVEATDLEPEAQESNKTK
FREAWNMVSTADGILIPGGFGVRGTEGMVLAARWARENHIPFLGVCLGLQ
IATIEFTRSVLGRKDSHSAEFYPDIDEKNHVVVFMMRLGLRPTFFQNETE
WSQIKKLYGDVSEVHERHRHRYEINPKMVDELENNGLIFVGKDDTGKRCE
ILELKNHPYYIATQYHPEYTSKVLDPSKPFLGLVAASAGILQDVIEGKYD
LEA
3D structure
PDB7rmv Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
ChainA
Resolution6.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.2: CTP synthase (glutamine hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UTP A Q190 K191 T192 K193 Q190 K191 T192 K193
BS02 ATP A G13 G15 K16 G17 V18 R215 V242 G13 G15 K16 G17 V18 R215 V242
BS03 UTP A S12 P41 E155 S12 P41 E155
Gene Ontology
Molecular Function
GO:0003883 CTP synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0042802 identical protein binding
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0006541 glutamine metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0019856 pyrimidine nucleobase biosynthetic process
GO:0044210 'de novo' CTP biosynthetic process
Cellular Component
GO:0000324 fungal-type vacuole
GO:0005737 cytoplasm
GO:0097268 cytoophidium

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rmv, PDBe:7rmv, PDBj:7rmv
PDBsum7rmv
PubMed34734801
UniProtP28274|URA7_YEAST CTP synthase 1 (Gene Name=URA7)

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