Structure of PDB 7ri0 Chain A

Receptor sequence
>7ri0A (length=430) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
PISKIHARSVYDSRGNPTVEVDVVTETGLHRAIVPSGASTGQHEAHELRD
GDKTQWGGKGVLKAVKNVNETIGPALIKENIDVKDQSKVDEFLNKLDGTA
NKSNLGANAILGVSLAVAKAGAAEKGVPLYAHISDLAGTKKPYVLPVPFQ
NVLNGGSHAGGRLAFQEFMIVPDSAPSFSEALRQGAEVYQKLKALAKKKY
GQSAGNVGDEGGVAPDIQTAEEALDLITEAIEQAGYTGKIKIAMDVASSE
FYKADVKKYDLDFKKWLTYEQLADLYKSLAAKYPIVSIEDPFAEDDWEAW
SYFYKTSDFQIVGDDLTVTNPGRIKKAIELKSCNALLLKVNQIGTLTESI
QAAKDSYADNWGVMVSHRSGETEDVTIADIAVGLRSGQIKTGAPCRSERL
AKLNQILRIEEELGENAVYAGSKFRTAVNL
3D structure
PDB7ri0 A structural model of the human plasminogen and Aspergillus fumigatus enolase complex.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D246 E297 D322 D245 E289 D314
BS02 2PG A A39 S40 H159 Q167 E168 E211 D246 D322 K347 H375 R376 S377 K398 A38 S39 H158 Q166 E167 E210 D245 D314 K339 H367 R368 S369 K390
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
GO:0019863 IgE binding
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ri0, PDBe:7ri0, PDBj:7ri0
PDBsum7ri0
PubMed35247004
UniProtQ96X30|ENO_ASPFU Enolase (Gene Name=enoA)

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