Structure of PDB 7rhq Chain A

Receptor sequence
>7rhqA (length=974) Species: 8355 (Xenopus laevis) [Search protein sequence]
LRAFFQRQLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLRAANLETNVEEL
WVEVGGRVSRELDYTRQKIGEEAMFNPQLMIQTPLEDGANVLTTEALLQH
LHSALEATKVQVYMYNKPWKLEELCFKSGELITEAVYVSQIIDSMYPCLI
ITPLDCFWEGAKLQSGMAYLPGKDILQWTNFDPLELLEELKKGKLHIDIW
EEMINKAEVGHGYMDRPCLNPSDKNCPYTAPNKNSTKPVDVSLILSGGCY
GLSKKYMHWQEELIIGGTVKNASGQIVSALALQTMFQLMTPKQMYEHFKG
HEVVSHMNWNEDKAAAILEAWQRTYVQVVHQSVPQNSSQKVLPFTTTTLD
DILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCAKSQGAVGLAGVLLVA
LSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQN
KRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAA
VVVVFNFAMVLLIFPAILSMDLYRREVSSFAEKHYAPFLLKPKTKVAVIL
GFLALLSVSLYGTTRVRDGLDLTDIVPRETREYDFIATQFKYFSFYHMYV
VTQKADYPRAQRLLYELHKSFVGVRYVLLEGNKQLPKMWLHYFRDWLQGL
QDTFDHEWEAGKITRNDYRNASDDAVLAYKLLIQTGNSDKPINLNQLTKQ
RLVDADGIIQPNAFYIYLTAWVSNDPVAYAASQANIRPHPPEWLHDKADD
RPETRTIRAAEPIEYVQFPFYLNGLRETSDFVEAIEKVRAICNNYTSLGV
SSYPNGYPFLFWEQYISLRHWLLLSISVVLACTFLVCALFLLNPWTAGII
VMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLT
AVGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVL
AILTLLGVLNGLVLLPVLLSFFGP
3D structure
PDB7rhq Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex.
ChainA
Resolution3.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR A L106 A109 V427 F485 L38 A41 V359 F417
BS02 Y01 A Y214 W268 Y146 W200
Gene Ontology
Molecular Function
GO:0008158 hedgehog receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7rhq, PDBe:7rhq, PDBj:7rhq
PDBsum7rhq
PubMed35231446
UniProtQ98SW6

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