Structure of PDB 7rhj Chain A

Receptor sequence
>7rhjA (length=450) Species: 9606 (Homo sapiens) [Search protein sequence]
VVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDY
VSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIP
TDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVM
YIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYW
STLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNA
ARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLK
YLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDY
ICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGS
KAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMK
3D structure
PDB7rhj Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
ChainA
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG A F544 G545 E546 I547 S548 R561 T562 A563 I602 F389 G390 E391 I392 S393 R406 T407 A408 I447
BS02 5H0 A T361 T362 G385 A390 V393 T206 T207 G230 A235 V238
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rhj, PDBe:7rhj, PDBj:7rhj
PDBsum7rhj
PubMed34699778
UniProtP29973|CNGA1_HUMAN Cyclic nucleotide-gated channel alpha-1 (Gene Name=CNGA1)

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