Structure of PDB 7rgx Chain A

Receptor sequence
>7rgxA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
MLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB7rgx Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia.
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 57I A R144 H158 N160 R162 W181 E184 R32 H46 N48 R50 W69 E72
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:7rgx, PDBe:7rgx, PDBj:7rgx
PDBsum7rgx
PubMed35427125
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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