Structure of PDB 7rg7 Chain A

Receptor sequence
>7rg7A (length=264) Species: 32630 (synthetic construct) [Search protein sequence]
NPSLIRSESWSVASGNEANLLDGDDNTGVWYKNHHHWESLAGEFIGLDLG
KEIKLDGIRFVIGKNGGGSSDKWNKFKLEYSLDNESWTTIKEYDKTGAPA
GKDVIEESFETPISAKYIRLTNLEAAPAHLTFSEFAIVSDQVQLVESGGG
LVQAGGSLRLSCAASRRSSRSWAMAWFRQAPGKEREFVAKISGDGRLTTY
GDSVKGRFTISRDNAEYLVYLQMDSLKPEDTAVYYCAADDNYVTASWRSG
PDYWGQGTQVTVSS
3D structure
PDB7rg7 Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices.
ChainA
Resolution1.83 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MTX A V176 A198 R200 R201 S202 S203 R204 W206 R246 N248 Y251 L252 V253 V142 A164 R166 R167 S168 S169 R170 W172 R212 N214 Y217 L218 V219
BS02 MG A N19 D22 D24 T27 S133 E134 N19 D22 D24 T27 S133 E134
BS03 MG A D274 D286 D240 D252
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