Structure of PDB 7rdv Chain A

Receptor sequence
>7rdvA (length=181) Species: 10090 (Mus musculus) [Search protein sequence]
EADHVGFYGTTVYQSPGDIGQYTHEFDGDELFYVDLDKKKTVWRLPEFGQ
LILFEPQGGLQNIAAEKHNLGILTKRSNFTPATNEAPQATVFPKSPVLLG
QPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKLSY
LTFIPSDDDIYDCKVEHWGLEEPVLKHWTSG
3D structure
PDB7rdv TFH TCR bound to MHC Class II IAd presenting aggrecan epitope
ChainA
Resolution2.90007 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y8 H24 I52 F54 G58 Q61 N62 A65 N69 I72 R76 Y8 H24 I52 F54 G58 Q61 N62 A65 N69 I72 R76
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7rdv, PDBe:7rdv, PDBj:7rdv
PDBsum7rdv
PubMed
UniProtP04228|HA2D_MOUSE H-2 class II histocompatibility antigen, A-D alpha chain (Gene Name=H2-Aa)

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