Structure of PDB 7rdf Chain A

Receptor sequence

>7rdfA (length=375) Species: 208964 (Pseudomonas aeruginosa PAO1)

MIEADYLVIGAGIAGASTGYWLSAHGRVVVLEREAQPGYHSTGRSAAHYT
VAYGTPQVRALTAASRAFFDNPPAGFCEHPLLSPRPEMVVDFSDDPEELR
RQYESGKALVPQMRLLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDAL
HQGYLRGIRRNQGQVLCNHEALEIRRVDGAWEVRCDAGSYRAAVLVNAAG
AWCDAIAGLAGVRPLGLQPKRRSAFIFAPPPGIDCHDWPMLVSLDESFFL
KPDAGMLLGSPANADPVEAHDVQPEQLDIATGMYLIEEATTLTIRRPEHT
WAGLRSFVADGDLVAGYAANAEGFFWVAAQGGYGIQTSAAMGEASAALIR
HQPLPAHLREHGLDEAMLSPRRLSP

3D structure

• PDB: 7rdf Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase.
• Chain: A
• Resolution: 1.29 Å

Enzymatic activity

• Enzyme Commision number: 1.4.99.6: D-arginine dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	4R2	A	I9 G10 G12 I13 A14 L31 E32 R33 H40 S41 T42 R44 S45 A46 H48 Y53 E87 E170 A171 A199 G200 W202 R222 F249 G303 R305 Q330 G331 G332 Y333 G334 I335 Q336	I9 G10 G12 I13 A14 L31 E32 R33 H40 S41 T42 R44 S45 A46 H48 Y53 E87 E170 A171 A199 G200 W202 R222 F249 G303 R305 Q330 G331 G332 Y333 G334 I335 Q336
BS02	6FA	A	I9 G10 G12 I13 A14 E32 R33 H40 S41 T42 S45 A46 H48 E170 A171 A199 G200 W202 R222 G303 R305 Q330 G331 G332 Y333 G334 I335 Q336	I9 G10 G12 I13 A14 E32 R33 H40 S41 T42 S45 A46 H48 E170 A171 A199 G200 W202 R222 G303 R305 Q330 G331 G332 Y333 G334 I335 Q336

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008718 D-amino-acid dehydrogenase activity
• GO:0016491 oxidoreductase activity

Biological Process

• GO:0006525 arginine metabolic process
• GO:0006527 arginine catabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:7rdf, PDBe:7rdf, PDBj:7rdf
• PDBsum: 7rdf
• PubMed: 34864048
• UniProt: Q9HXE3|DAUA_PSEAE FAD-dependent catabolic D-arginine dehydrogenase DauA (Gene Name=dauA)