Structure of PDB 7rd0 Chain A

Receptor sequence
>7rd0A (length=482) Species: 645463 (Clostridioides difficile R20291) [Search protein sequence]
EKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKKAT
KMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYA
KDGLLSHTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKTVDNKDK
DRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQ
NDISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYN
CTGKTKVGNTNEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEK
ILKSAEKLHLFEKVDIGLDEEKIREAPKNISIRNLAIGQENIEFTPLQIN
QMTQIIANNGTFKPLYLYKSLVDNNMNTIKTYKSSKKEELISPYVCTQVK
EYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKKAIDHGWITGFYPEE
RPKYVITVLVEGTQKGNKSATPIFKEICESIK
3D structure
PDB7rd0 A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.129: Transferred entry: 2.4.99.28.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C323 C338 H344 C357 C251 C266 H272 C285
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0071555 cell wall organization
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rd0, PDBe:7rd0, PDBj:7rd0
PDBsum7rd0
PubMed35902581
UniProtQ18B92

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