Structure of PDB 7rcx Chain A

Receptor sequence
>7rcxA (length=811) Species: 645463 (Clostridioides difficile R20291) [Search protein sequence]
APRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKLIN
LLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFY
YLVDKLISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDK
RDWLASYKLSAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGY
SQYNPVTIAKDVGETTIAQIEESAMDLVGVSIAVEPVRYYPNGSLASHML
GYVGKMPSTQIESYLQKGYETGDMVGLAGVEKSNESRLRGTDGYIESKKP
KSGDTVYLTLDKDLQEVSDNALKQIIEVASKGGTFKSKFGDKPISAYAGK
AQSAALIAIDVKNGEVLASSSYPNYDPNKFAKGISTEDYLAGSPLLNLVT
QGEFQPGSSFKMLTSMAALENGLDPNFTINDPGVIMLGKKSFGDYVWNHG
RGNHGMTNLYKAIQESCNIYMATIGTGKTWPDGKSIGIDMNANKILEYAK
LFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLENFAKWSTADT
FNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRAVSSDYSSVKIN
DQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKTGTA
EKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEK
EIKKKLENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELN
PKITDDQIDRFKQDYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLP
TREVIGTYMGL
3D structure
PDB7rcx A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile.
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.129: Transferred entry: 2.4.99.28.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D515 D528 H538 C551 D431 D444 H454 C467
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0071555 cell wall organization
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rcx, PDBe:7rcx, PDBj:7rcx
PDBsum7rcx
PubMed35902581
UniProtQ18B08

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