Structure of PDB 7r9c Chain A

Receptor sequence
>7r9cA (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELP
3D structure
PDB7r9c A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2IR A P82 F83 V87 L92 Y97 M132 C136 N140 I146 P41 F42 V46 L51 Y56 M91 C95 N99 I105
External links
PDB RCSB:7r9c, PDBe:7r9c, PDBj:7r9c
PDBsum7r9c
PubMed35007061
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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