Structure of PDB 7r0e Chain A

Receptor sequence
>7r0eA (length=709) Species: 1318616 (Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9))) [Search protein sequence]
GMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFASICTHLEVCFMYS
DFHFIDERGESTIILKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLP
DLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMAT
KADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEI
TGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARI
EPFLRTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDA
IKCMKTFFGWKEPNIIKPHEKGINPNYLLTWKQVLAELQDIENEEKIPRT
KNMKKTSQLKWALGENMAPEKVDFEDCKDVNDLKQYDSDEPEPRSLACWI
QSEFNKACELTDSSWVELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATE
YIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKG
RSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAVGQV
SRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDL
TKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEG
FSAESRKLLLIVQALRDNLEPGTFDLEGLYEAIEECLINDPWVLLNASWF
NSFLTHALR
3D structure
PDB7r0e Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
ChainA
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075523 viral translational frameshifting
GO:0075526 cap snatching
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7r0e, PDBe:7r0e, PDBj:7r0e
PDBsum7r0e
PubMed36596301
UniProtM9TI86

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