Structure of PDB 7qwj Chain A

Receptor sequence
>7qwjA (length=298) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPI
LLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSL
ETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKT
FTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLL
CDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVV
EDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPA
3D structure
PDB7qwj Crystal structure of Glc7 phosphatase
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D91 N123 H172 H247 D91 N123 H172 H247
BS02 MN A D63 H65 D91 D63 H65 D91
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0017018 myosin phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0000076 DNA replication checkpoint signaling
GO:0000077 DNA damage checkpoint signaling
GO:0000282 cellular bud site selection
GO:0000723 telomere maintenance
GO:0005977 glycogen metabolic process
GO:0005979 regulation of glycogen biosynthetic process
GO:0006397 mRNA processing
GO:0006873 intracellular monoatomic ion homeostasis
GO:0006986 response to unfolded protein
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0007116 regulation of cell budding
GO:0007346 regulation of mitotic cell cycle
GO:0008360 regulation of cell shape
GO:0009408 response to heat
GO:0030437 ascospore formation
GO:0030837 negative regulation of actin filament polymerization
GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled
GO:0031297 replication fork processing
GO:0031536 positive regulation of exit from mitosis
GO:0034501 protein localization to kinetochore
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051726 regulation of cell cycle
GO:0070873 regulation of glycogen metabolic process
GO:1901901 regulation of protein localization to cell division site involved in cytokinesis
GO:1903501 positive regulation of mitotic actomyosin contractile ring assembly
GO:1904547 regulation of cellular response to glucose starvation
GO:2000370 positive regulation of clathrin-dependent endocytosis
Cellular Component
GO:0000131 incipient cellular bud site
GO:0000164 protein phosphatase type 1 complex
GO:0000776 kinetochore
GO:0001400 mating projection base
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005816 spindle pole body
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex
GO:0005935 cellular bud neck
GO:0032153 cell division site
GO:0032174 cellular bud neck septin collar

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qwj, PDBe:7qwj, PDBj:7qwj
PDBsum7qwj
PubMed
UniProtP32598|PP12_YEAST Serine/threonine-protein phosphatase PP1-2 (Gene Name=GLC7)

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