Structure of PDB 7qv8 Chain A

Receptor sequence
>7qv8A (length=208) Species: 5671 (Leishmania infantum) [Search protein sequence]
EIIMVTTGSREVDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLP
ISQGGAEGMALYIDTEGTFRPERLVAVAARYGLDPEDVLANVACARAFNT
DHQQQLLLQASAMMAENRFALIVVDSATALYRTDYSGRNELAARQMHLGK
FLRSLHNLAEEYGVAVVVTNQVSTTRLSLRKGRGEQRIIKVYDAEAIFGI
YDDGVGDA
3D structure
PDB7qv8 Divergent binding mode for a protozoan BRC repeat to RAD51.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L194 L222 V225 A226 C227 A228 H235 Q242 M246 E249 L61 L89 V92 A93 C94 A95 H102 Q109 M113 E116
BS02 MG A T170 E199 D258 T37 E66 D125
BS03 ADP A F165 R166 T167 G168 K169 T170 Q171 E345 R347 I366 Y367 D368 F32 R33 T34 G35 K36 T37 Q38 E185 R187 I200 Y201 D202
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:7qv8, PDBe:7qv8, PDBj:7qv8
PDBsum7qv8
PubMed35502837
UniProtA4I3C9

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