Structure of PDB 7qn7 Chain A

Receptor sequence
>7qn7A (length=335) Species: 9606 (Homo sapiens) [Search protein sequence]
ENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTM
DVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNM
TAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAY
PKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIV
MTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITT
VLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTN
IQMEKTSKIDKYARILFPVTFGAFNMVYWVVYLSK
3D structure
PDB7qn7 Differential assembly diversifies GABA A receptor structures and signalling.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ABU A R100 T163 R55 T118
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004890 GABA-A receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006821 chloride transport
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qn7, PDBe:7qn7, PDBj:7qn7
PDBsum7qn7
PubMed35355020
UniProtP48169|GBRA4_HUMAN Gamma-aminobutyric acid receptor subunit alpha-4 (Gene Name=GABRA4)

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