Structure of PDB 7qkn Chain A

Receptor sequence
>7qknA (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
ESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWC
STEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYKGKF
DVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIS
SYKHTTSIFDDFAHYEKRQAVVEVVRKERQSRNK
3D structure
PDB7qkn Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 JVF A D401 R404 C412 D39 R42 C50
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:7qkn, PDBe:7qkn, PDBj:7qkn
PDBsum7qkn
PubMed36268123
UniProtQ9BYJ9|YTHD1_HUMAN YTH domain-containing family protein 1 (Gene Name=YTHDF1)

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