Structure of PDB 7qi1 Chain A

Receptor sequence
>7qi1A (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSMTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLS
VAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICN
DVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNS
QQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTA
FDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWT
3D structure
PDB7qi1 Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N44 K51 R58 R129 Y130 L174 N175 Y181 E182 T207 E211 S212 Y213 N226 W230 N47 K54 R61 R132 Y133 L177 N178 Y184 E185 T210 E214 S215 Y216 N229 W233
BS02 Q95 A R58 S59 R62 V63 R61 S62 R65 V66
BS03 Q95 A G55 A56 S59 S60 G58 A59 S62 S63
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