Structure of PDB 7qgs Chain A

Receptor sequence
>7qgsA (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
GSADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLN
HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA
3D structure
PDB7qgs Understanding p300-transcription factor interactions using sequence variation and hybridization.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H347 C351 C364 C369 H20 C24 C37 C42
BS02 ZN A H378 C382 C388 H51 C55 C61
BS03 ZN A H402 C406 C411 C414 H75 C79 C84 C87
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7qgs, PDBe:7qgs, PDBj:7qgs
PDBsum7qgs
PubMed35656479
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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