Structure of PDB 7qfw Chain A

Receptor sequence
>7qfwA (length=823) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
IDINTKIFNSVAEVFQKAQGSYAGHRKHIAVLKKIQSKAVEQGYEDAFNF
WFDKLVTKILPLKKNEIIGDRIVKLVAAFIASLERELILAKKQNYKLTND
EEGIFSRFVDQFIRHVLRGVESPDKNVRFRVLQLLAVIMDNIGEIDESLF
NLLILSLNKRIYDREPTVRIQAVFCLTKFQDEEQTEHNFEATRTLVASIQ
NDPSAEVRRAAMLNLINDNNTRPYILERARDVNIVNRRLVYSRILKSMGR
KCFDDIEPHIFDQLIEWGLEDRELSVRNACKRLIAHDWLNALDGDLIELL
EKLDVSRSSVCVKAIEALFQSRPDILSKIKFPESIWKDFTVEIAFLFRAI
YLYCLDNNITEMLEENFPEASKLSEHLNHYILLRYHHNHFDYNTLEFIIE
QLSIAAERYDYSDEVGRRSMLTVVRNMLALTTLSEPLIKIGIRVMKSLSI
NEKDFVTMAIEIINDIRDDDIEKQEQEEKEKEASSATIVLCLTRSSYMLE
LVNTPLTENILIASLMDTLITPAVRNTAPNIRELGVKNLGLCCLLDVKLA
IDNMYILGMCVSKGNASLKYIALQVIVDIFSVHGNTVVDGEGKVDSISLH
KIFYKVLKNNGLPECQVIAAEGLCKLFLADVFTDDDLFETLVLSYFSPIN
SSNEALVQAFAFCIPVYCFSHPAHQQRMSRTAADILLRLCVLWDDLQSSV
IPEVDREAMLKPNIIFQQLLFWTDPRNLVNQTGSTKKDTVQLTFLIDVLK
IYAQIEKKEIKKMIITNINAIFLSSEQDYSTLKELLEYSDDIAENDNLDN
VSKNALDKLRNNLNSLIEEINER
3D structure
PDB7qfw A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
ChainA
Resolution3.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K70 N71 R170 R224 N800 Q804 T853 N854 N856 A857 K64 N65 R164 R209 N713 Q717 T766 N767 N769 A770
BS02 dna A S27 Y28 K131 N248 N887 V888 N891 S21 Y22 K125 N233 N800 V801 N804
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0007076 mitotic chromosome condensation
GO:0007130 synaptonemal complex assembly
GO:0010032 meiotic chromosome condensation
GO:0030261 chromosome condensation
GO:0051301 cell division
GO:0051307 meiotic chromosome separation
GO:0070058 tRNA gene clustering
GO:0070550 rDNA chromatin condensation
GO:1903342 negative regulation of meiotic DNA double-strand break formation
Cellular Component
GO:0000793 condensed chromosome
GO:0000796 condensin complex
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qfw, PDBe:7qfw, PDBj:7qfw
PDBsum7qfw
PubMed35653469
UniProtQ06680|CND3_YEAST Condensin complex subunit 3 (Gene Name=YCG1)

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