Structure of PDB 7qcl Chain A

Receptor sequence
>7qclA (length=546) Species: 9606 (Homo sapiens) [Search protein sequence]
PPECPDTWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVED
PDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDN
FGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQAVAL
PYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQ
CGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPDCTPSPLCQ
LIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQ
NICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEG
CFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGG
SGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKE
KPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKC
QDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKC
3D structure
PDB7qcl The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.
ChainA
Resolution3.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC A N4738 T4740 N343 T345
BS02 GAL A P4402 P4405 P34 P37
BS03 FUC A N4906 N4907 N511 N512
BS04 CA A D4444 T4575 T4577 T4579 D4582 D4583 D76 T203 T205 T207 D210 D211
External links
PDB RCSB:7qcl, PDBe:7qcl, PDBj:7qcl
PDBsum7qcl
PubMed37031240
UniProtQ02817|MUC2_HUMAN Mucin-2 (Gene Name=MUC2)

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