Structure of PDB 7q9w Chain A

Receptor sequence
>7q9wA (length=133) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
SKNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKG
QVVQTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDDIYA
WLKRAGKFKATQRTEGVSTTDLIVRILKNYEDY
3D structure
PDB7q9w Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.15: choline-phosphate cytidylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9NN A L670 S688 L56 S74
BS02 GZ6 A D623 W692 D9 W78
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
Biological Process
GO:0006657 CDP-choline pathway
GO:0009058 biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7q9w, PDBe:7q9w, PDBj:7q9w
PDBsum7q9w
PubMed
UniProtQ8IEE9

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