Structure of PDB 7q8c Chain A

Receptor sequence
>7q8cA (length=370) Species: 5664 (Leishmania major) [Search protein sequence]
SSIVCDNGSGMVKAGFSGDDAPRHVFPSIVGRPKNMQAMMGSANKTVYVG
DEAQSKRGVLSLKYPIEHGIVTNWDDMEKIWHHTFYNELRVNPEQHNVLL
TEAPMNPKQNREKMTQIMFETFNVPSLYIGIQAVLSLYSSGRTTGIVLDA
GDGVTHTVPIYEGYSLPHAVRRVDMAGRDLTEYLMKIMMETGTTFTTTAE
KEIVRNVKEQLCYVALDFEEEMTNSAKSANEEAFELPDGNVMMVGNQRFR
CPEVLFKPSLIGLDEAPGFPEMVYQSINKCDIDVRRELYGNIVLSGGSTM
FLNLPERLAKEISNLAPSSIKPKVVAPPERKYSVWIGGSILSSLTTFQTM
WVKKSEYDESGPSIVHNKCF
3D structure
PDB7q8c Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.
ChainA
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A G13 G15 G156 D157 K213 E214 G302 M305 F306 G8 G10 G151 D152 K208 E209 G297 M300 F301
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton

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Molecular Function
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Cellular Component
External links
PDB RCSB:7q8c, PDBe:7q8c, PDBj:7q8c
PDBsum7q8c
PubMed35705539
UniProtP45520|ACT_LEIMA Actin

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