Structure of PDB 7q86 Chain A

Receptor sequence

>7q86A (length=612) Species: 9606 (Homo sapiens)

MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHED
LNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKNFVHRGRPEPL
DLHLGMFLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGL
ETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCY
GLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRE
NMLMKYAQVKPDGTYVKMVFVRSFLVGEAARALSKACTIAIRYSAVRHQS
EIKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRISPELH
ALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFE
GENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPMVDINSPESLTE
AYKLRAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVV
VKLFSEKLLKIQDKAIQAVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQI
TQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEW
AKNSPLNKAEVH

3D structure

• PDB: 7q86 Crystal structures of apo- and FAD-bound human peroxisomal acyl-CoA oxidase provide mechanistic basis explaining clinical observations.
• Chain: A
• Resolution: 2.09 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	T139 G144 T145 W176 P177 T419 F420 E423	T139 G144 T145 W176 P177 T398 F399 E402
BS02	FAD	A	R307 S310 F324 K330 A395 G397 G398	R297 S300 F314 K320 A374 G376 G377

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 30 06:58:24 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '7q86', asym_id = 'A', title = 'Crystal structures of apo- and FAD-bound human p...hanistic basis explaining clinical observations. '

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='7q86', asym_id='A', title='Crystal structures of apo- and FAD-bound human p...hanistic basis explaining clinical observations. ')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0003997,0005504,0005777,0006631,0006635,0016627,0033540,0050660,0071949', uniprot = '', pdbid = '7q86', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003997,0005504,0005777,0006631,0006635,0016627,0033540,0050660,0071949', uniprot='', pdbid='7q86', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>