Structure of PDB 7q6x Chain A

Receptor sequence
>7q6xA (length=397) Species: 1890 (Streptomyces antibioticus) [Search protein sequence]
ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSD
ARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGK
AFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICEL
LGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDA
PTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLL
LTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVT
VRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQ
LGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW
3D structure
PDB7q6x Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A V93 L94 H101 A244 G245 T248 Q252 R298 A348 F349 H354 C356 I357 G358 V83 L84 H91 A234 G235 T238 Q242 R288 A338 F339 H344 C346 I347 G348
BS02 DEB A F84 L94 A244 S295 F74 L84 A234 S285
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7q6x, PDBe:7q6x, PDBj:7q6x
PDBsum7q6x
PubMed35053203
UniProtQ59819

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