Structure of PDB 7q4i Chain A

Receptor sequence
>7q4iA (length=279) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
ENSTIAERLYSEVRVLCWIMTNPSNHQKKARHVKRTWGKRCNKLIFMSSA
KDDELDAVALPVGEGRNNLWGKTKEAYKYIYEHHINDADWFLKADDDTYT
IVENMRYMLYPYSPETPVYFGCKFKPYVKQGYMSGGAGYVLSREAVRRFV
VEALPNPKLCKSDNSGAEDVEIGKCLQNVNVLAGDSRDSNGRGRFFPFVP
EHHLIPSHTDKKFWYWQYIFYKTDEGLDCCSDNAISFHYVSPNQMYVLDY
LIYHLRPYGIINTPDALPNKLAVGELMPE
3D structure
PDB7q4i Structural basis for the synthesis of the core 1 structure by C1GalT1.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.122: N-acetylgalactosaminide beta-1,3-galactosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R152 Y213 W300 Y304 Y325 R66 Y127 W214 Y218 Y239
BS02 UDP A M106 N108 E150 G151 R152 L155 D181 D182 D183 H324 Y325 M20 N22 E64 G65 R66 L69 D95 D96 D97 H238 Y239
BS03 MN A D181 D183 H324 D95 D97 H238
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7q4i, PDBe:7q4i, PDBj:7q4i
PDBsum7q4i
PubMed35504880
UniProtQ7K237|C1GLT_DROME Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (Gene Name=C1GalTA)

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