Structure of PDB 7q3w Chain A

Receptor sequence
>7q3wA (length=133) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
SKNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKG
QVVQTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDDIYA
WLKRAGKFKATQRTEGVSTTDLIVRILKNYEDY
3D structure
PDB7q3w Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.15: choline-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8R1 A F644 E645 F30 E31
BS02 8R1 A K770 D774 K128 D132
BS03 8R1 A D623 T654 K663 W692 H709 D9 T40 K49 W78 H95
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
Biological Process
GO:0006657 CDP-choline pathway
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7q3w, PDBe:7q3w, PDBj:7q3w
PDBsum7q3w
PubMed
UniProtQ8IEE9

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