Structure of PDB 7q3m Chain A

Receptor sequence
>7q3mA (length=131) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
SKNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKG
QVVQTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDDIYA
WLKRAGKFKATQRTEGVSTTDLIVRILKNYE
3D structure
PDB7q3m Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors.
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.15: choline-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GZ6 A M628 L629 M14 L15
BS02 GZ6 A E685 Y702 E71 Y88
BS03 GZ6 A K660 V666 K46 V52
BS04 8O9 A D623 G624 W692 D9 G10 W78
BS05 8O9 A D623 Y626 D9 Y12
BS06 8O9 A D705 K749 D91 K107
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
Biological Process
GO:0006657 CDP-choline pathway
GO:0009058 biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7q3m, PDBe:7q3m, PDBj:7q3m
PDBsum7q3m
PubMed
UniProtQ8IEE9

[Back to BioLiP]