Structure of PDB 7q2i Chain A

Receptor sequence
>7q2iA (length=134) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
SKNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKG
QVVQTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDEDIY
AWLKRAGKFKATQRTEGVSTTDLIVRILKNYEDY
3D structure
PDB7q2i Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.15: choline-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XHG A Y706 K749 Y92 K108
BS02 XHG A D623 T654 W692 D9 T40 W78
BS03 GZ6 A E685 I687 E71 I73
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
Biological Process
GO:0006657 CDP-choline pathway
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7q2i, PDBe:7q2i, PDBj:7q2i
PDBsum7q2i
PubMed
UniProtQ8IEE9

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