Structure of PDB 7q2d Chain A

Receptor sequence
>7q2dA (length=286) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
TRFEDIQAHYDVSDDFFALFQDPTRTYSCAYFEPPELTLEEAQYAKVDLN
LDKLDLKPGMTLLDIGCGWGTTMRRAVERFDVNVIGLTLSKNQHARCEQV
LASIDTNRSRQVLLQGWEDFAEPVDRIVSIEAFEHFGHENYDDFFKRCFN
IMPADGRMTVQSSVSYHPYEMAARGKKLSFETARFIKFIVTEIFPGGRLP
STEMMVEHGEKAGFTVPEPLSLRPHYIKTLRIWGDTLQSNKDKAIEVTSE
EVYNRYMKYLRGCEHYFTDEMLDCSLVTYLKPGAAA
3D structure
PDB7q2d Fragment-Based Ligand Discovery Applied to the Mycolic Acid Methyltransferase Hma (MmaA4) from Mycobacterium tuberculosis : A Crystallographic and Molecular Modelling Study.
ChainA
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZZT A E146 F148 F151 G152 S177 F209 L214 E131 F133 F136 G137 S162 F194 L199
BS02 ZZT A R40 W84 R111 R25 W69 R96
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0008610 lipid biosynthetic process
GO:0032259 methylation
GO:0071768 mycolic acid biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7q2d, PDBe:7q2d, PDBj:7q2d
PDBsum7q2d
PubMed34959681
UniProtQ79FX8|MMAA4_MYCTU Hydroxymycolate synthase MmaA4 (Gene Name=mmaA4)

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