Structure of PDB 7q1c Chain A

Receptor sequence
>7q1cA (length=427) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
LPPPVAIIVGHNIDASAMPLTYERNRFVIDMLQHYACPVFSHVSSDVFEW
VLEPFPVVGVEDMTAFHDRAYLNYLSIREALSEVDERASTVKPPLRVLPD
LVPIPADEEYGLVNENMPFVGMWRTIQATVSGTLLAARLLAQPGRFAAIH
WFGGRHHAKKSTAGGFCFANDVVLGVLELKKLLSSDKNGILVVDVDAHHG
DGTQSAFLHDNSVLTLSMHAHGVGIFPGTGGIEEIGAGLGRGFTMNVPLP
EGATDILAVTLMYRSIHFAFKKLGEGLAAIVIVCGSDALSGDPLGALNLT
VGGMQSIIRLLLKEAARRSLKVLLLGAGGYVDTSCARLAGVVTKDVLSCA
AAMRLGKTEYFGDSANLGDNLGVAVPEGCEYFTRYGPSFLMHGLPPARVS
KLYRLPYGSPLFMRMQRAATKEALRRR
3D structure
PDB7q1c Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D237 H239 D328 D196 H198 D287
BS02 T56 A E156 H197 H198 F207 D237 H239 Y371 E115 H156 H157 F166 D196 H198 Y330
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