Structure of PDB 7pve Chain A

Receptor sequence
>7pveA (length=133) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
SKNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKG
QVVQTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDDIYA
WLKRAGKFKATQRTEGVSTTDLIVRILKNYEDY
3D structure
PDB7pve Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors
ChainA
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.15: choline-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ES3 A D623 W692 D9 W78
BS02 ES3 A E685 Y702 E71 Y88
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
Biological Process
GO:0006657 CDP-choline pathway
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7pve, PDBe:7pve, PDBj:7pve
PDBsum7pve
PubMed
UniProtQ8IEE9

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