Structure of PDB 7prt Chain A

Receptor sequence

>7prtA (length=384) Species: 9606 (Homo sapiens) [Search protein sequence]

FKNSTYSRSSVDVLYTFANCSGLDLIFGLNALLRTADLQWNSSNAQLLLD
YCSSKGYNISWELGNEPNSFLKKADIFINGSQLGEDFIQLHKLLRKSTFK
NAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYLNGRTATRED
FLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTF
AAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLL
FKKLVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHN
VTKYLRLPYPFSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLP
PLMEKPLRPGSSLGLPAFSYSFFVIRNAKVAACI

3D structure

PDB

7prt Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.

Chain

Resolution

1.7 Å

3D
structure

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Enzymatic activity