Structure of PDB 7pp0 Chain A

Receptor sequence
>7pp0A (length=233) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SGEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDE
LLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAA
GVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAH
STDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQH
YPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR
3D structure
PDB7pp0 1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-beta-Lactamase Inhibitors.
ChainA
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H114 H116 H179 H85 H87 H150
BS02 ZN A D118 C198 H240 D89 C169 H211
BS03 7ZN A W87 H116 D118 H179 C198 G209 N210 H240 W58 H87 D89 H150 C169 G180 N181 H211
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7pp0, PDBe:7pp0, PDBj:7pp0
PDBsum7pp0
PubMed35050549
UniProtQ9K2N0

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