Structure of PDB 7pou Chain A

Receptor sequence
>7pouA (length=346) Species: 817 (Bacteroides fragilis) [Search protein sequence]
VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKI
QLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMN
EIAEFYAAPFKKTRAINEKEAFECIYDSRTGKYPVSVKINVDKAKKILNL
PECDYINDYIKTPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAV
HGLKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIY
FLIRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELG
HILGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD
3D structure
PDB7pou Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis.
ChainA
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D194 H348 H352 H358 D158 H297 H301 H307
BS02 6JP A L225 Y265 T266 K292 A293 L174 Y214 T215 K241 A242
BS03 PRO A S44 Y45 T46 K127 S11 Y12 T13 K94
BS04 PRO A G118 D178 G372 Y373 G85 D142 G321 Y322
BS05 PRO A D39 Q41 K65 N67 D6 Q8 K32 N34
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7pou, PDBe:7pou, PDBj:7pou
PDBsum7pou
PubMed36173175
UniProtO86049

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