Structure of PDB 7poq Chain A

Receptor sequence
>7poqA (length=344) Species: 817 (Bacteroides fragilis) [Search protein sequence]
VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKI
QLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMN
EIAEFYAAPFKKTRAINEKEAFECIYDSKYPVSVKINVDKAKKILNLPEC
DYINDYIKTVPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHG
LKRYVNLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFL
IRWGTWDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHI
LGANHADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD
3D structure
PDB7poq Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis.
ChainA
Resolution1.85 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D194 H348 H352 H358 D155 H295 H299 H305
BS02 7WK A Y221 I223 L225 Y265 A293 Y296 Y301 Y168 I170 L172 Y212 A240 Y243 Y248
BS03 PRO A G118 D178 G372 Y373 G85 D139 G319 Y320
BS04 PRO A Y45 T46 Y126 K127 V171 Y12 T13 Y93 K94 V132
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7poq, PDBe:7poq, PDBj:7poq
PDBsum7poq
PubMed36173175
UniProtO86049

[Back to BioLiP]