Structure of PDB 7pol Chain A

Receptor sequence
>7polA (length=339) Species: 817 (Bacteroides fragilis) [Search protein sequence]
VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKI
QLDNENVRLFNGRDKDSTNFILGDEFAVLRFYRNGESISYIAYKEAQMMN
EIAEFYAAPFKKTRAINEKEAFECIYDSRKYPVSVKINVDKAKKILNLPE
CDYINPSEPKTVYVICLRENGSTVYPNEVSAQMQDAANSVYAVHGLKRYV
NLHFVLYTTEYACPSGNADEGLDGFTASLKANPKAEGYDDQIYFLIRWGT
WDNNILGISWLNSYNVNTASDFKASGMSTTQLMYPGVMAHELGHILGANH
ADDPKDLMYSKYTGYLFHLSEKNMDIIAKNLGWEIADGD
3D structure
PDB7pol Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H348 H352 H290 H294
BS02 7X9 A L225 Y265 K292 A293 Y296 L167 Y207 K234 A235 Y238
BS03 7X9 A Y221 Y296 Y163 Y238
BS04 PRO A Y45 T46 K127 V171 Y12 T13 K94 V133
BS05 PRO A D360 D361 D302 D303
BS06 PRO A L377 E379 L319 E321
BS07 7X9 A T50 D54 T17 D21
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7pol, PDBe:7pol, PDBj:7pol
PDBsum7pol
PubMed36173175
UniProtO86049

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