Structure of PDB 7pla Chain A

Receptor sequence

>7plaA (length=437) Species: 34078 (Scytonema hofmannii) [Search protein sequence]

NASQITIQARLISFESNRQQLWKLMADLNTPLINELLCQLGQHPSTVVSQ
LCQPLKTDPPSRLYMSAIHIVDYIYKSWSLPFPLVFETNEDMVWSKNQKG
RLCVHFNGLSDLIFEVYCGNRQLHWFQRFLEDQQTKRKSKNQHSSGLFTL
RNGHLVWLEGEGKGEPWNLHHLTLYCCVDNRLWTEEGTEIVRQEKADEIT
KFITNMKKKSDLSDTQQALIQRKQSTLTRINNSFERPSQPLYQGQSHILV
GVSLGLEKPATVAVVDAIANKVLAYRSIKQLLGDNYELLNRQRRQQQYLS
HERHKAQKNFSPNQFGASELGQHIDRLLAKAIVALARTYKAGSIVLPKLG
DMREVVQSEIQAIAEQKFPGYIEGQQKYAKQYRVNVHRWSYGRLIQSIQS
KAAQTGIVIEEGKQPIRGSPHDKAKELALSAYNLRLT

3D structure

PDB

7pla Target site selection and remodelling by type V CRISPR-transposon systems.

Chain

Resolution

3.04 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	A	T5 Q7 R9 I11 S12 R17 I90 R300 L301 Y316 C317 G318 N319 R320 Q321 L322 H323 H353 K362 H369 W382 P436 Y474 S476 K478 Q479 N489 R493 Q496 H500 H503 K504 E518 L519 H522 R525 L526 K529 Y577 Q580 Y581 N584 H586 K600 Q603 H620	T6 Q8 R10 I12 S13 R18 I74 R101 L102 Y117 C118 G119 N120 R121 Q122 L123 H124 H154 K163 H170 W183 P237 Y275 S277 K279 Q280 N290 R294 Q297 H301 H304 K305 E319 L320 H323 R326 L327 K330 Y378 Q381 Y382 N385 H387 K401 Q404 H421
BS02	dna	A	Q3 Y89 E286 T287 N288 S343 S344 G345 R350 N351 C376 Q420 R421 S424 T425 S589	Q4 Y73 E87 T88 N89 S144 S145 G146 R151 N152 C177 Q221 R222 S225 T226 S390
BS03	dna	A	S77 R78 V292 N306 S309 R336 K339 M405 T414 R421	S61 R62 V93 N107 S110 R137 K140 M206 T215 R222

External links

PDB	RCSB:7pla, PDBe:7pla, PDBj:7pla
PDBsum	7pla
PubMed	34759315
UniProt	A0A8X6EH11

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