Structure of PDB 7phw Chain A

Receptor sequence
>7phwA (length=317) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
RHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQ
KKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKD
MTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLIC
GVSPYKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKND
LSFHFYVGVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYI
VSYGNDNNFAECYIFFNNENSILIKPEKYAGCYGGTFVKIDENRALFIYS
SSQGIYNIHTIYYANYE
3D structure
PDB7phw Heterotypic interactions drive antibody synergy against a malaria vaccine candidate.
ChainA
Resolution2.793 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E120 E122 E90 E92
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
GO:0005515 protein binding
Biological Process
GO:0044409 symbiont entry into host
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0020002 host cell plasma membrane
GO:0020009 microneme
GO:0031410 cytoplasmic vesicle
GO:0032991 protein-containing complex
GO:0034494 microneme lumen
GO:0043655 host extracellular space
GO:0045177 apical part of cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7phw, PDBe:7phw, PDBj:7phw
PDBsum7phw
PubMed35177602
UniProtQ8IFM8|CYRPA_PLAF7 Cysteine-rich protective antigen (Gene Name=CyRPA)

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